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This gene is really a member in the SUMO gene loved ones. This family of genes encode little ubiquitin-related modifiers that happen to be attached to proteins and Management the focus on proteins' subcellular localization, steadiness, or action. The protein described in this record is located in the cytoplasm and precisely modifies IKBA, resulting in detrimental regulation of NF-kappa-B-dependent transcription of your IL12B gene.

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